Sofosbuvir is used in combination with other antiviral drugs for treatment of patients with viral infection that damages the liver (Hepatitis C) including those patients who have human immunodeficiency virus (HIV) infection or liver cancer or are awaiting a liver transplant.
Hepcvir-1 concentrations were generally observed approximately 1 to 2 hours post-dose.
Administration of a high-fat meal reduced Cmax and AUC by 28% and 23%, respectively.
Administration of a light meal did not influence daclatasvir exposure. Daclatasvir exposure HCV
infected subjects appeared to be lower than those observed in healthy volunteers at repeated
doses from 1 to 30 mg, but similar at 60 mg.
Avoid taking an antacid within 4 hours before or 4 hours after you take Harvoni. This especially includes antacids that contain aluminum or magnesium (Acid Gone, Aldroxicon, Alternagel, Di-Gel, Gaviscon, Gelusil, Genaton, Maalox, Maldroxal, Milk of Magnesia, Mintox, Mylagen, Mylanta, Pepcid Complete, Rolaids, Rulox, and others).
Taking this medication will not prevent you from passing hepatitis C to other people. Do not have unprotected sex or share razors or toothbrushes. Talk with your doctor about safe ways to prevent HCV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.
Chills, ulcers, sores, nausea, pale skin, lower back or side pain, trouble sleeping., unusual tiredness or weakness, diarrhea, fever, muscle pain/ cramps, mouth ulcers, skin rash/ itching, decreased appetite, headache