TemoNat(Temozolomide) (tem-oh-ZOHL-oh-mide) belongs to the general group of medicines known as antineoplastics. It is used to treat specific types of cancer of the brain in adults whose tumors have returned and whose tumors have just been diagnosed.

TemoNat(Temozolomide) seems to interfere with the growth of cancer cells, which are then eventually destroyed by the body. Since the growth of normal body cells may also be affected by TemoNat(Temozolomide), other effects will also occur. Some of these may be serious and must be reported to your doctor.

Before you begin treatment with TemoNat(Temozolomide), you and your doctor should talk about the good this medicine will do as well as the risks of using it.

The recommended dose of temonat is usually once daily for 5 days. The treatment may be repeated every 28 days.

Temonat should not be taken without consulting your doctor if you have kidney disease, liver disease, blood disorders such as low white blood cell counts or low blood platelet levels, allergies (especially to dacarbazine). Temonat may lower the body's ability to fight an infection. Do not take temonat if you are allergic to it or to any ingredient in temonat and to dacarbazine.

Do not take temonat without consulting your doctor if you are pregnant.

Along with its needed effects, TemoNat(Temozolomide) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Less common or rare

• Amnesia
• black, tarry stools
• blood in urine or stools;
• convulsions (seizures);
• cough or hoarseness;
• fever or chills; infection;
• lower back or side pain;
• muscle weakness or paralysis on one or both sides of the body;
• painful or difficult urination;
• pinpoint red spots on skin;
• swelling of feet or lower legs;
• unusual bleeding or bruising