Zytiga (abiraterone) works by reducing androgen production in the body. Androgens are male hormones that can promote tumor growth in the prostate gland.
Zytiga is used together with prednisone to treat prostate cancer that has spread to other parts of the body.
Zytiga is used in men whose prostate cancer cannot be treated with surgery or other medicines.
Zytiga is usually taken once per day while also taking prednisone two times per day. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Your prednisone dosage needs may change if you have surgery, are ill, or are under stress. Do not change your medication dose or schedule without your doctor's advice.
Take this medicine on an empty stomach. Do not eat anything for at least 2 hours before you take Zytiga and for at least 1 hour after you have taken the medicine.
Do not crush, chew, or break a tablet. Swallow the tablet whole with a full glass of water.
Your blood pressure will need to be checked often, and you may need frequent blood tests at your doctor's office.
You should not stop using Zytiga or prednisone suddenly. Follow your doctor's instructions about tapering your prednisone dose.
Store at room temperature away from moisture and heat.
Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.
Warning & Precautions
You should not use Zytiga if you are allergic to abiraterone, or if you have:
severe liver disease.
To make sure Zytiga is safe for you, tell your doctor if you have:
heart disease, high blood pressure;
a history of problems with your adrenal gland or pituitary gland;
low levels of potassium in your blood;
a history of fluid retention;
if you have recently had a heart attack; or
if you take medicine to treat seizures, tuberculosis, HIV or AIDS.
While you are taking Zytiga and for at least 1 week after your treatment ends:
If your sexual partner is pregnant - Use a condom to prevent transfer of this medication to her.
If your sexual partner could become pregnant - Use a condom plus another form of effective birth control to prevent pregnancy.
Although Zytiga is not for use by women, this medicine can harm an unborn baby or cause birth defects. Zytiga tablets should not be handled by a woman who is pregnant or who may become pregnant. If this cannot be avoided, the woman should wear latex gloves.
It is not known whether abiraterone passes into breast milk or if it could harm a nursing baby. Abiraterone should not be used by a woman who is breast-feeding a baby.
This medicine is not approved for use by anyone younger than 18 years old.
bloating or swelling of the face, arms, hands, lower legs, or feet
bloody or cloudy urine
chest pain or discomfort
difficult, burning, or painful urination